Caption: Mycobacterium paratuberculosis - Gram-positive, rod prokaryote (dividing). Genetically M. paratuberculosis is almost identical to Mycobacterium avium. However phenotyically it grows much more slowly, requires an iron-transport chemical known as mycobactin for in vitro growth, forms rough colonies on solid agar media, and infects mammals instead of birds. While sharing many genetic similarities with M. avium, M. paratuberculosis is less closely linked genetically to pathogenic mycobacteria in the TB complex. M. paratuberculosis can grow only inside animal cells where it assimilates iron from its host's cells, most often immune cells called macrophages. Like other mycobacteria, M. paratuberculosis has the capacity to thrive inside macrophages. Thus, it is an obligate parasitic pathogen of mammals; a zoonotic microorganism that most commonly infects ruminant animals. Also associated with Johne's disease.
Magnification*: x3,000
Type: SEM
Copyright 2002 Dennis Kunkel Microscopy, Inc.
Keywords: 22141A,11.01.02,animal disease,bacilli,bacillus,bacteria,bacterial pathogen,bacterium,dividing,division,gram positive,Gram-positive,Johne's disease,Mycobacterium avium,Mycobacterium paratuberculosis,prokaryote,rod,rod shaped,TB,tuberculosis,zoonoses,zoonotic disease,zoonotic microorganism,SEM