Caption: Bone lacuna and canaliculi from a fractured compact bone. Bone lacunae (upper mid region of photo) are bone cavities that are formed by osteoblasts (bone-producing cells). During bone formation osteoblasts become progressively trapped in the bone matrix at sites called lacunae. The osteoblast produces osteoid, the organic bone matrix that is a mass of collagen fibers and glycoprotein cement. As soon as osteoid is formed, calcium salts crystallize inside it to form mineralized, compact bone (seen here in this image). Osteoblasts that become trapped in lacunae in the bone become osteocytes. The osteocyte has many processes or thread-like extensions that enter the bone through the bone canaliculi (green), a network of minute channels linking nearby lacunae. Compact bone is made of collagen fibers and ground substances arranged in concentric sheets.
Magnification*: x2,600
Type: SEM
Copyright 2008 Dennis Kunkel Microscopy, Inc.
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