Caption: Parasitic promastigotes that cause leishmaniasis in humans (Leishmania braziliensis). This tropical protozoan disease is transmitted by bites from infected sand flies (insect vector). The parasites are ingested by the insect vector during a blood meal from a mammal or human. The parasites in humans are found within macrophages in the amastigote form. In the blood stream they transform into the promastigote form. Promastigotes multiple by longitudinal fission in the gut of the insect. Leishmaniasis occurs in two forms: cutaneous which affects the skin and mucous membranes, usually giving rise to an ulcer at the site of the insect bite. Some patients develop a more destructive and progressive infection in mucosal tissue. The more serious kala-azar causes fever and liver damage, and it can be fatal.
Magnification*: x2,200
Type: SEM
Copyright 2010 Dennis Kunkel Microscopy, Inc.
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