Caption: Hepatitis B virus (HBV) is the cause of "serum hepatitis" or hepatitis B. Human hepatitis B virus is the prototype virus of the Hepadnavirus family and is a DNA virus (partly double stranded). The complete virus or virion is called a Dane particle (approx. 40 nanometers in diameter). The virus attacks the liver, producing liver inflammation, flu-like symptoms, followed by jaundice. The inflammation is the immune response to the virus invading liver cells and replicating. The virus has a coat (capsid) bearing surface glycoproteins, which the body detects as foreign substances (antigenic determinants). It is spread by infected blood through blood transfusions, tattooing, acupuncture, and needle sharing by intravenous drug abusers. Hepatitis B is also a sexually transmitted disease. Hepatitis C (HCV) is similar in morphology to Hepatitis B. It however belongs to the Flavivirus family and is an RNA virus (single stranded; yellow fever is prototype). Hepatitis C virus is associated with chronic liver disease and also with primary liver cancer in some countries. It is most commonly spread by blood contact, through blood transfusions or shared infected needles. It causes inflammation of the liver with jaundice and flu-like symptoms. Four million Americans are infected with hepatitis C. There is currently no vaccine for hepatitis C.
Magnification*: x52,880
Type: SEM
Copyright 2004 Dennis Kunkel Microscopy, Inc.
Keywords: 18588A,06.01.04,antigen,antigens,capsid,dane particle,Dane particles,DNA virus,Flavivirus,glycoprotein,HBV,HCV,Hepadnavirus,hepatitis b,hepatitis c,hepatitis virus,human disease,jaundice,liver infection,protein coat,RNA virus,virion,virions,virus,virus pathogen,viruses,TEM