920409-03

920409-03
Caption: Vitamin B6 (pyridoxine) crystals. Vitamin B6 is a water-soluble vitamin that exists in three major chemical forms: pyridoxine, pyridoxal, and pyridoxamine. In the liver pyridoxine and pyridoxamine are converted to pyridoxal 5'-phosphate (PLP) which is a cofactor in many reactions of amino acid metabolism. PLP also is necessary for the enzymatic reaction governing the release of glucose from glycogen. Vitamin B6 is needed for more than 100 enzymes involved in protein metabolism. It is also essential for red blood cell metabolism. The nervous and immune systems need vitamin B6 to function efficiently, and it is also needed for the conversion of tryptophan to niacin (Vitamin B3). Vitamin B6 deficiency can result in pyroluria. An overdose of pyridoxine can cause a temporary deadening of certain nerves such as the proprioceptory nerves, causing a feeling of dissembodiment common with the loss of proprioception.
Magnification*: x40
Type: LM
Copyright 1985 Dennis Kunkel Microscopy, Inc.
Keywords: 920409-03,12.01.04,crystal,crystals,B vitamin,B vitamin complex,B-complex vitamin,glycogen metabolism,niacin,pyridoxine,pyridoxamine,pyridoxal,liver pyridoxine,pyroluria,proprioceptory nerves,proprioception,protein metabolism,red blood cell metabolism,tryptophan,Vitamin B6,Vitamin B6 deficiency,LM