Caption: Plasmodium falciparum plasmodial young schizont infecting an erythrocyte (red blood cell). Note the red blood cell membrane has small distinct knobs (purple) that are characteristic of the infection by certain strains of Plasmodium falciparum. The young schizont stage cytoplasm has a distinct food vacuole (light brown) with hemozoin pigment granules (red). The cytoplasm contains two nuclei (ivory), mitochondria (pink) and ribosomes (orange). In addition Maurer's clefts (blue) can be seen in the red blood cell hemoglobin-containing cytoplasm. Malaria is caused by Plasmodium spp., parasitic single-celled protozoans called plasmodia. Malaria is spread to humans by species of tropical mosquitoes (Anopheles species). Infection spreads from the liver to the blood, where the plasmodium multiplies inside red blood cells. The plasmodial parasite reproduces asexually in the red blood cells significantly destroying many red blood cells. There are four stages of the parasite that develop in human red blood cells - merozoite stage, ring stage, trophozoite stage and schizont stage. Release of mature Plasmodium merozoites results in further infection and produces bouts of shivering fever (paroxysms) and sweating that may be fatal.
Magnification*: x3,810
Type: TEM
Copyright 2007 Dennis Kunkel Microscopy, Inc.
Keywords: medical,blood,blood cells,red blood cells,malaria,schizont,RBC,plasmodium,blood infection,human disease,infected red blood cell,infected red blood cells,infected human blood,human blood,malaria infected red blood cell,knobby red blood cell,knobby red blood cell membrane,knobby cell membrane,knobby variant,malaria infected red blood cells,malaria infection,malaria schizont stage,Plasmodium falciparum,plasmodium schizont stage,red blood cell,schizont stage,dividing schizont stage,malaria parasite,malaria parasites,protozoa,protozoan,paroxysms,chills,disease vector,erythrocyte,erythrocytes,fever,insect vector,malaria vector,TEM,07.01.07,plasmodia,parasite,parasitic,protozoans,asexual reproduction,RBCs,liver infection,plasmodial parasite,hemozoin,hemozoin pigment,hemozoin pigment granule,hemozoin pigment granules,hemozoin pigments,knobby cell,blood cell,Maurer's cleft,Maurer's clefts,Maurers cleft,Maurers clefts,251904E